Screening for Aldose Reductase Inhibitory Activity of Extracts of the Marine Plants from Korea

doi:2004.19.4.349

Algae > Volume 19(4); 2004 > Article

Algae 2004;19(4): 349-352. doi: https://doi.org/10.4490/ALGAE.2004.19.4.349

Yeon Sil Lee, Sanghyun Lee¹^,*, Bak-Kwang Kim¹ and Kuk Hyun Shin

Seokwon Life Science Research Institute, World Sea Green Co. Ltd., Paju 413-832, and
¹College of Pharmacy, Seoul National University, Seoul 151-742, Korea

ABSTRACT

We examined MeOH extracts of the marine plants from Korea for their inhibitory activities on rat lens aldose reductase in vitro. Among the MeOH extracts tested, the extracts of Enteromorpha prolifera, Ecklonia cava, Pelvetia siliquosa and Salicornia herbacea exhibited a rat lens aldose reductase inhibition (IC: 3.04, 8.84, 11.42 and 4.99 g-ml, respectively) in vitro.

Key words: aldose reductase activity; Ecklonia cava; Enteromorpha prolifera; Pelvetia iliquosa; Salicornia herbacea; marine plant